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The dosage is determined by patient Illinois shipping cephalexin 250mg weight and can be administered orally or via gastrostomy tube. The most common adverse reactions reported with trofinetide were diarrhea and vomiting. The product, which received FDA approval in March 2023, was approved based on data from the pharmacy to measure and deliver the prescribed dose accurately. Findings showed that treatment with trofinetide led to statistically significant improvements on the Rett Syndrome Behaviour Questionnaire total score and the Clinical Global Impression-Improvement score at week 12 compared with placebo (coprimary endpoints). Daybue is supplied as a strawberry-flavored oral solution containing 200 mg of trofinetide per mL.
Findings showed that treatment with trofinetide led to statistically significant improvements on the Rett Syndrome Behaviour Questionnaire total score and the Clinical Global Impression-Improvement score at week 12 compared with placebo (coprimary endpoints).
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